Dermatologist Dr. Macrene Alexiades Lets Us Into Her Beauty Cabinet

Phebe Wahl | July 16, 2019 | Style & Beauty


“There is a duality to my mind and abilities: artist and scientist,” says Dr. Macrene Alexiades, founder and director of Dermatology and Laser Surgery Center of New York. Alexiades—who began working in the lab at the mere age of 12 and entered her freshman year at Harvard at 16—launched her own skincare brand, Dr. Macrene 37 Actives, in 2009. The line debuted with a waiting list of hundreds—all coveting the hero cream, which originally contained only 37 actives, but now has over 50. “My main objective,” she says, “is to use my expertise, knowledge and extensive work in lasers and injectables in dermatology to make procedures obsolete by transferring these effects into the skin via active ingredients, and I believe I have achieved this goal.” Here, the top doc shares some of her beauty bests.


1. “For mascara, currently, I am fond of Diorshow, as it has impressive staying power!” Diorshow mascara, $30, by Dior at Sephora, Ala Moana Center;


2. “As for makeup, I am a lover of NARS (I heard he loves my brand back) and use his lip colors almost daily.” Orgasm oil-infused lip tint, $26, by Nars at Sephora, Ala Moana Center;


3. “I am a Lancôme girl for years (I am their dermatologist of record) and use their eye palettes almost exclusively, which are superb.” Lancôme Hypnôse palette in Terre de Sienne, $50, by Lancôme at Nordstrom, Ala Moana Center;


4. “At night, I wash with 37 Actives cleansing treatment and apply my cream, serum, lip, and neck and dec [products]. I sleep on high-count cotton pillowcases with drops of lavender for good dreams.” High performance anti-aging cleanser, $79, by Dr. Macrene 37 Actives at


5. “Start young to stay young, and believe in science and plant actives. The patients in my practice who have gotten the best results and have the most beautiful skin are hands down the ones who religiously apply 37 Actives hero cream twice a day every day.” High performance anti-aging cream, $295, by Dr. Macrene 37 Actives at


6 “You need to understand what each supplement is for and use it when you need it. For example, if I get a joint pain, I will take my turmeric and drink a nettle tea; if I am traveling by air, I take a glutathione to combat the increased radiation; if I feel a cold coming on, I dose 2 grams of vitamin C with bioflavonoids.”


7 “My daily routine is: wash with lukewarm water; apply 37 Actives moisturizer, then the serum on top. My formulations are top of the line, and that is why the cream goes on first (it is all liposomes, which penetrate immediately), and serum adds firming ability with more peptides and more actives, but goes on top.” High performance anti-aging and firming serum, $175, by Dr. Macrene 37 Actives at


Photography by: Portrait by Ondrea Barbe | product photos courtesy of brands | vitamin C photo by SIRICHAYAPAT CHAIWATCHARANON/istock photo